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Elevated estradiol

14 posts in this topic

I recently did a hormone test, with testosterone sitting at at 691.2 ng/dl (24 nmol/L) and estradiol at 40 pg/ml (147 pmol/L). The E2 is just below the upper ref limit in Sweden, which at 150 is way too generous IMO. I think my 147 is far too much and I need to lower it. I'd like to cut it in half at least. Is that possible without pharmaceutical aromatase inhibitors?

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My estradiol (the most potent estrogen) is too high. It's made by an enzyme called aromatase, which converts testosterone into estradiol. Block the aromatase, and the latter goes down while the former goes up. I need that or I won't function properly.

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It's extremely unlikely that any Swedish doctor will prescribe Arimidex, which is what I need to correct this gross excess of estradiol. I'll probably have to move to the US to get it legally, which will take years. In the meantime I'll be forced to live as a hormonal hermaphrodite or risk going to jail for buying it illegally.

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There are several doctors -- including some Objectivists -- who can consult with you and even prescribe for you over the internet. What I would advise against is self-diagnosis or self-medication for complex medical issues requiring in-depth knowledge and extensive clinical experience.

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That sounds good. Wonder how much it'd cost to have them look at my blood work results and offer an opinion based on symptoms, history etc.

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Unfortunately American prescriptions are not valid in Sweden, but perhaps a doctor's recommendation could help me sway a particularly cooperative local doc.

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...Unless it could be arranged for an Objectivist doctor to have a German colleague do it. For all I know that might be ridiculously farfetched in terms of policy, but technically speaking it shouldn't be a problem with the right connections. (Sorry for triple post)

This is a problem that's been plaguing me for years. My body composition, libido, and general drive are messed up because of it. In 2010 I measured low testosterone but that has since increased. It's only now that I got my estradiol done and just like I suspected it's very high. All my medical problems going back 10 years make sence in the light of this.

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Here are two ideas for you. Based on what you have posted above, you probably are already doing the first one.

Most of the medical research in the USA is reported on government websites. To find the latest information about any condition, go to Google Advanced Search, enter your search terms, and restrict the search to the .gov domain. For example, I input "elevated estradiol" as a phrase, entered "men" and "male" in the "any of these words" box, and ".gov" in the "site or domain" box.

The English healthcare system is mostly nationalized. However, there is a private segment called BUPA. London is a major destination for medical toruism. Perhaps a doctor there could help you with your situation.

I echo Betsy's advice. By all means research and learn about your condition. But, for treatment, put yourself in the hands of a qualified doctor.

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You could try some lifestyle changes. I am not sure exactly what causes your high estradiol levels, but I have read that at least the following can all impact the aromatization of testosterone into estrogen, or the production of t. to start with:

- diet: testosterone requires saturated fat and cholesterol.

- stress levels / sleep quality: low stress, good sleep quality is required to produce testosterone.

- Weight lifting: heavy weight lifting promotes testosterone (endurance work doesn't)

- High body fat levels contributes to aromatization.

Also, there's some evidence that consuming content of an erotic nature boosts testosterone (although maybe only temporarily).... :-)

The problem with supplementing is that once you go that route, you might have to continuously do so, or maybe increase the dose over time. Hormones are tricky that way.

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Oh, in the diet adjustment: selenium is also needed (best source: seafood).

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I've been lifting for 3 years, I'm 6'1" tall, and I weigh 190 lbs. As mentioned I've increased my T, which by itself has had positive effects. But if anything that will give aromatase even more material to convert into yet more estrogen.

I don't think anastrozole use would be problematic. as long as my levels are kept at a healthy 40-60 or so. 147 is "80 year old demasculinized shell of a man" territory.

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Look into a supplement called tribulus. I take it in phases. I don't know about the availability of such supplements is in Sweden.

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